Which of following is not seen in nephritic syndrome-
**Core Concept**
Nephritic syndrome is characterized by inflammation of the glomeruli, leading to hematuria, proteinuria, and hypertension. The condition is often associated with immune complex deposition and complement system activation.
**Why the Correct Answer is Right**
The hallmark of nephritic syndrome is the presence of hematuria, which is caused by the breakdown of the glomerular basement membrane due to immune complex deposition. This leads to the leakage of red blood cells into the urine. Proteinuria, although present, is typically less severe compared to nephrotic syndrome. The condition is often accompanied by hypertension, which is a result of the activation of the renin-angiotensin-aldosterone system in response to the decreased glomerular filtration rate.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because hematuria is a characteristic feature of nephritic syndrome.
**Option B:** This option is incorrect because proteinuria, although less severe, is still present in nephritic syndrome.
**Option C:** This option is incorrect because hypertension is a common complication of nephritic syndrome.
**Clinical Pearl / High-Yield Fact**
Nephritic syndrome is often associated with a rapid decline in renal function, which can lead to end-stage renal disease if left untreated. It is essential to differentiate nephritic syndrome from nephrotic syndrome, as the two conditions require different treatment approaches.
**Correct Answer:** D.