Which NSAID can cause hyperuricemia?
Correct Answer: Ibuprofen
Description: ASPIRIN can cause hyperuricemia depending on dose used. At low doses :1-2g/day -decrease uricacid excretion and hence cause hyperuricemia. It also blocks the effects of probencid and other uricosuric drugs. Intermediate doses:2-3g/day-No effect Large doses:>5g/day-uricosuric 1st most commonly used NSAID in hyperurecemia ahritis (gout) is NAPROXONE 2nd most commonly used is IBUPROFEN ref : maheswari th ed
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