**Core Concept**
Rhabdomyolysis is a serious syndrome characterized by the breakdown of skeletal muscle, leading to the release of myoglobin into the bloodstream. This can cause acute kidney injury, electrolyte imbalances, and potentially life-threatening complications. The condition often results from direct or indirect muscle injury, which triggers the release of lysosomal enzymes and the subsequent destruction of muscle tissue.
**Why the Correct Answer is Right**
Rhabdomyolysis can be caused by various factors, including excessive exercise, muscle trauma, or the use of certain medications that affect muscle function. Statins, a class of cholesterol-lowering medications, can cause rhabdomyolysis as a rare but serious side effect. This occurs when statins inhibit the enzyme HMG-CoA reductase, leading to an imbalance in muscle cell metabolism and potentially triggering muscle damage.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is not provided.
* **Option B:** While certain medications like beta-agonists can cause muscle cramps or weakness, they are not typically associated with rhabdomyolysis.
* **Option C:** This option is not provided.
* **Option D:** This option is not provided.
**Clinical Pearl / High-Yield Fact**
It is essential to recognize the warning signs of rhabdomyolysis, including muscle pain or weakness, dark urine, and electrolyte imbalances, and to promptly seek medical attention if these symptoms occur.
**Correct Answer: A. Statins.**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.