Which joint is spared in Rheumatoid arthritis –
Now, the question is about which joint is spared. The classic "spared" joint in RA is the distal interphalangeal (DIP) joint. This is a key point because in RA, the PIP joints are affected, but the DIPs are typically not. In contrast, osteoarthritis often affects the DIPs, leading to Heberden's nodes. Another joint that might be spared is the hip, but I think the more classic answer is the DIP. Wait, but sometimes other options are given. Let me check the standard answer. Yes, the DIP joints are the ones usually spared in RA. So the correct answer would be the DIP joint. The options probably include DIP as an option.
The distractors might be MCP, PIP, wrist, or maybe the knee. The user didn't list the options, but based on the correct answer, the DIP is the spared joint. Now, explaining why the others are incorrect: MCP and PIP are commonly affected in RA. The wrist is also a typical site. The knee is another common joint involved. So the key is that RA doesn't typically affect the DIPs. That's a classic differentiator from osteoarthritis. The clinical pearl here is that RA spares the DIPs, while OA affects them. That's a high-yield point for exams.
**Core Concept**
Rheumatoid arthritis (RA) is a systemic autoimmune disorder characterized by symmetric synovitis, predominantly affecting small joints of the hands and feet. The *distal interphalangeal (DIP) joints* are **spared** in RA, distinguishing it from osteoarthritis, which commonly involves DIPs.
**Why the Correct Answer is Right**
RA typically targets **proximal interphalangeal (PIP)**, **metacarpophalangeal (MCP)**, and **metatarsophalangeal (MTP)** joints. The **DIP joints** are spared due to differences in synovial membrane vulnerability and immune-mediated inflammation patterns. This sparing is a key clinical clue to differentiate RA from other arthritides like psoriatic arthritis or osteoarthritis.
**Why Each Wrong Option is Incorrect**
**Option A:** *MCP joints* are early and commonly affected in RA due to their synovial structure and mechanical use.
**Option B:** *PIP joints* are hallmark targets of RA, leading to the classic "swan-neck" deformity.
**Option C:** *Wrist joints* are frequently involved in RA, often presenting with synovitis and carpal tunnel syndrome.
**Clinical Pearl / High-Yield Fact**
Remember: **RA spares DIPs, but