Which is the screening test for acromegaly?
Correct Answer: Serum IGF-1
Description: The screening test for acromegaly is Serum IGF-1 levels. IGF-2 is responsible for prenatal growth. Oral glucose tolerance test with GH obtained at 0, 30 and 60 minutes. Normal people can supress growth hormone to <1g/L. Due to pulsatile nature of GH secretion, measurement of a single random value is not useful for diagnosis or exclusion of acromegaly.
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