Which is the most impoant element in treatment of diphtheria?
Correct Answer: Antitoxin
Description: The most impoant element in treatment of diphtheria is antitoxin. Option 1 1. Treatment of diphtheria: Treatment should be staed immediately on clinical suspicion of diphtheria. 2. Anti-diphtheritic horse serum or ADS (antitoxin): It is the treatment of choice as it neutralizes the toxin. Serum antitoxin concentration of 0.01 IU/mL is usually accepted as the minimum protective level, and 0.1 IU/mL provides a definitely protective level. NOTE- Antitoxin appears to be of no value in treatment of cutaneous diphtheria. Option 2, 3, 4 1. Antibiotics: Penicillin or erythromycin is the drug of choice. Antibiotic plays a minor role as it is of no use once the toxin is secreted. However, antibiotics are useful: - If given early (< 6 hrs of infection), before the toxin release. - Prevent fuher release of toxin by killing the bacilli. - Treatment for cutaneous diphtheria. 2. Treatment of carriers: Drug of choice is erythromycin.
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Microbiology
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