Which is the most common cytogenetic abnormality in adult myelodysplastic syndrome (MDS) –
Correct Answer: 5q?
Description: Answer is C (5q-) `Monosomy 7 is by far the most common cytogenetic abnormality in children (pediatric MDS) whereas 5q- is observed most frequent!,' in adults' - Myelodysplastic Syndromes by John Bennett (2002)/300 Cytogenetic Abnormalities in MDS: Facts to Remember Monosomy 7 is the most frequent cytogenetic abnormality in children.Q Deletion 5q (5q) is the most frequent cytogenetic abnormality in adults Q. Trisomy 8 is the most frequent tri.somyQ. Differences between Myelodysplastic Syndromes in children and Adults (`Myelodysplastic Syndromes' 2002/300; 'Childhood Leukemias' 2'"/549) Feature Children Adults * Frequency Less common More common * Presence of sideroblasts Uncommon (<2%) More common (,--25%) * Cytogenetic Abervations -7/7q- Most common (r,30%) Less common (,=-40%) -5/5q- Uncommon (--L-1-2%) Most common (z20%)
Category:
Medicine
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now