Which is the best way to manage a patient present with aspirin poisoning

Correct Answer: Make urine alkaline with NaHCO3
Description: Ans. (b) Make urine alkaline with NaHCO3Refi.KDT 6th ed. /16* Aspirin is an acidic drug, it readily crosses any acidic medium. To treat this toxicity, make the urine alkaline with NaHCO3.* Now, this acid drug can't be reabsorbed from the basic medium, and it readily gets excreted from the body.Also Know* In basic drug poisoning like amphetamine, we acidify the urine with NH4C1~ to change the medium, which opposes reabsorption and hence excretion.* N-acetyl cysteine is the DOC for paracetamol poisoning
Category: Pharmacology
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