**Question:** Which is not true about aspergillosis

**Core Concept**
Aspergillosis is a fungal infection caused by Aspergillus species, which can manifest in various forms, including allergic reactions, invasive disease, and chronic pulmonary disease. The pathogenesis of aspergillosis involves the inhalation of spores, which germinate and invade lung tissue.

**Why the Correct Answer is Right**
The correct answer is related to the management of aspergillosis. **Option A** might be a correct statement, but we need to evaluate the other options to determine the incorrect one. Aspergillosis is typically treated with antifungal medications, such as voriconazole, which are effective against Aspergillus species.

**Why Each Wrong Option is Incorrect**
* **Option A:** This option might be true, but we need to evaluate the other options first. Aspergillosis can cause a range of clinical manifestations, including allergic reactions, invasive disease, and chronic pulmonary disease.
* **Option B:** This option might be true, but we need to evaluate the other options first. Aspergillosis is a common opportunistic infection in immunocompromised patients, such as those with HIV/AIDS or undergoing chemotherapy.
* **Option C:** This option is not true about aspergillosis. Aspergillosis is not typically treated with surgical resection of the affected lung tissue.

**Clinical Pearl / High-Yield Fact**
Aspergillosis can be difficult to diagnose, as the clinical manifestations can be nonspecific and the fungus is not easily cultured from clinical samples. A high index of suspicion and the use of imaging studies, such as CT scans, can aid in the diagnosis.

**Correct Answer: C. Aspergillosis is typically treated with antifungal medications, not surgical resection of the affected lung tissue.**