Which is not major criteria for diagnosis of rheumatic fever ?
**Core Concept**
Rheumatic fever is an inflammatory disease that occurs after an infection with group A beta-hemolytic streptococci (GABHS). The diagnosis of rheumatic fever is based on the Jones criteria, which include major and minor criteria. The major criteria are manifestations that are directly related to the inflammatory process caused by the infection.
**Why the Correct Answer is Right**
The major criteria for the diagnosis of rheumatic fever include carditis, polyarthritis, chorea, erythema marginatum, and subcutaneous nodules. These manifestations are all directly related to the inflammatory process caused by the infection. The minor criteria include fever, arthralgia, and laboratory evidence of inflammation.
**Why Each Wrong Option is Incorrect**
**Option A:**
* This option is incorrect because it is not a major criterion for the diagnosis of rheumatic fever.
**Option B:**
* This option is incorrect because it is not a major criterion for the diagnosis of rheumatic fever.
**Option C:**
* This option is incorrect because it is not a major criterion for the diagnosis of rheumatic fever.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that the Jones criteria for diagnosing rheumatic fever have been updated over time, and the major criteria have remained relatively consistent.
**Correct Answer:** A.