Which is not a characteristic of wegeners granulomatosis?
Correct Answer: Involves large vessels
Description: Wegener granulomatosis is a necrotizing vasculitis characterizedby a specific triad of findings:* Granulomas of the lung and/or the upper respiratorytract (ear, nose, sinuses, throat)* Vasculitis of small to medium-sized vessels (capillaries,venules, aerioles, and aeries), most prominently inthe lungs and upper respiratory tract* GlomerulonephritisWegener granulomatosis is likely to be initiated as acell-mediated hypersensitivity response directed againstinhaled infectious or environmental antigens. PR3-ANCAsare present in almost 95% of cases and probably drive thesubsequent tissue injury.(Robbins basic pathology,9th edition,pg no.353)
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Pathology
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