Pathology Which is most commonly mutated gene in Surfactant Dysfunction Disorders: A Surfactant protein B B Surfactant protein C C GM-CSF D ATP-binding cassette protein member 3 (ABCA3) 💡 Explanation Which is most commonly mutated gene in Surfactant Dysfunction Disorders: ✓ Correct Answer: D. ATP-binding cassette protein member 3 (ABCA3)