## **Core Concept**
The question tests understanding of the cytochrome P450 (CYP450) enzyme system, specifically identifying a CYP450 inhibitor. CYP450 enzymes are crucial for metabolizing drugs, and inhibitors can significantly affect drug pharmacokinetics.
## **Why the Correct Answer is Right**
The correct answer, , is a known inhibitor of the cytochrome P450 enzyme system. CYP450 inhibitors work by binding to the active site of the enzyme, thereby reducing its ability to metabolize drugs. This can lead to increased levels of drugs that are normally metabolized by CYP450, potentially causing toxicity.
## **Why Each Wrong Option is Incorrect**
- **Option A:** is not typically classified as a CYP450 inhibitor; its primary mechanism or classification might differ.
- **Option B:** could potentially interact with CYP450 but is not identified as a primary inhibitor.
- **Option C:** might not have a significant inhibitory effect on the CYP450 system.
## **Clinical Pearl / High-Yield Fact**
A key clinical point to remember is that when a patient is taking a CYP450 inhibitor, doses of drugs that are substrates for the inhibited enzyme may need to be adjusted to prevent toxicity.
## **Correct Answer:** .
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.