Medical MCQ-Which is antigen presenting cell in the epidermis that is required for the induction of allergic contact dermatitis is:

Which is antigen presenting cell in the epidermis that is required for the induction of allergic contact dermatitis is:

Fibroblasts

Keratinocytes

Langerhans cells

Melanocytes

Question Category:

Dental

Correct Answer:

Langerhans cells

Description:

Langerhans' cell is a specialized antigen-presenting cell that help in antigen recognition and activation T cell mediated immune response. Functions - phagocytosis, antigen processing, antigen presentation, interaction with lymphocytes. Release IL-1 Langerhans cells are derived from mesoderm Langerhans cells are present in stratum spinosum Birbeck granules - rod or racquet shaped - contain Langerin Langerhans' cell decrease in (PSC) Psoriasis Sarcoidosis Contact dermatitis Langerhans' cell increase in - Langerhans Cell Histiocytosis

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