Which is a “Soft steroid” used in bronchial asthma?
Correct Answer: Ciclesonide
Description: A novel approach to minimizing the risk of toxicity from systemic absorption of an inhaled coicosteroid underlay the development of ciclesonide. This recently approved coicosteroid is inhaled as a prodrug activated by cleavage by esterases in bronchial epithelial cells. When absorbed into the circulation, the active product is tightly bound to serum proteins, and so has little access to glucocoicoid receptors in skin, eye, and bone, minimizing its risk of causing cutaneous thinning, cataracts, osteoporosis, or temporary slowing of growth.Katzung 12e pg: 348
Category:
Pharmacology
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