## Core Concept
The question tests knowledge of autoimmune diseases and their association with specific autoantibodies. Anti-phospholipase 2 receptor (anti-PLA2R) antibodies are specifically linked to a particular kidney disease. Phospholipase 2 receptors play a role in the regulation of the immune response.

## Why the Correct Answer is Right
The correct answer, **D.**, corresponds to Membranous Nephropathy (MN). Membranous nephropathy is a disease characterized by the formation of immune complexes on the subepithelial side of the glomerular basement membrane, leading to proteinuria. The presence of anti-PLA2R antibodies is a hallmark of primary membranous nephropathy, found in approximately 70-80% of patients. These antibodies target the M-type phospholipase 2 receptor on the podocytes, disrupting normal kidney function.

## Why Each Wrong Option is Incorrect
- **Option A:** Minimal Change Disease is characterized by nephrotic syndrome with minimal changes on light microscopy. It is not associated with anti-PLA2R antibodies but rather with immune complex deposition not being a feature.
- **Option B:** Focal Segmental Glomerulosclerosis (FSGS) is another cause of nephrotic syndrome but is not primarily associated with anti-PLA2R antibodies.
- **Option C:** IgA Nephropathy (Berger's disease) involves the deposition of IgA antibodies in the glomeruli and does not have a known association with anti-PLA2R antibodies.

## Clinical Pearl / High-Yield Fact
A key clinical pearl is that the detection of anti-PLA2R antibodies can help differentiate primary membranous nephropathy from secondary causes, guiding treatment decisions. Patients with positive anti-PLA2R antibodies may benefit from immunosuppressive therapy.

## Correct Answer Line
**Correct Answer: D. Membranous Nephropathy**