Which condition is Autosomal dominant
**Core Concept**
Autosomal dominant inheritance is a pattern of inheritance where a single copy of the mutated gene is sufficient to cause the condition. This means that if one parent has the mutated gene, each child has a 50% chance of inheriting it and expressing the condition.
**Why the Correct Answer is Right**
In autosomal dominant conditions, the mutated gene is located on one of the 22 non-sex chromosomes (autosomes) and does not require a second copy of the gene to be expressed. This is in contrast to autosomal recessive conditions, where two copies of the mutated gene are required. Examples of autosomal dominant conditions include neurofibromatosis type 1, achondroplasia, and Huntington's disease.
**Why Each Wrong Option is Incorrect**
**Option A:** This is actually an example of an autosomal recessive condition, where two copies of the mutated gene are required to express the condition.
**Option B:** This is a type of X-linked dominant condition, where the mutated gene is located on the X chromosome and can cause the condition in both males and females.
**Option C:** This is an example of an X-linked recessive condition, which primarily affects males who have only one X chromosome.
**Option D:** This is an example of a mitochondrial inheritance pattern, where the mutated gene is located in the mitochondria and can cause the condition in individuals with high levels of mitochondrial DNA.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that autosomal dominant conditions often have a higher penetrance than autosomal recessive conditions, meaning that individuals who inherit the mutated gene are more likely to express the condition.
**Correct Answer: B. This is a type of X-linked dominant condition, where the mutated gene is located on the X chromosome and can cause the condition in both males and females.**