Gynaecology & Obstetrics Which cardiovascular change is physiological in last trimester of pregnancy? A Mid-diastolic murmur B Occasional atrial fibrillation C Shift of apical impulse laterally and upwards in left 4th intercostal space D Cardiomegaly 💡 Explanation Which cardiovascular change is physiological in last trimester of pregnancy? ✓ Correct Answer: C. Shift of apical impulse laterally and upwards in left 4th intercostal space