Which antihypeensive is a prodrug and is conveed to its active form in brain?
Correct Answer: Methyl dopa
Description: Both methyldopa and minoxidil are prodrugs. Conversion of methyl dopa to a-methylnorepinephrine takes palce in the brain. Minoxidil is activated to minoxidil sulphate (by phase II reaction) in the periphery.
Category:
Pharmacology
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