Which Anti-viral drug causes the below given condition :
Correct Answer: Nelfinavir
Description: PROTEASE INHIBITORS - These drugs have adverse effects on Fat metabolism and redistribution on prolonged intake resulting in LIPODYSTROPHY SYNDROME (Buffalo hump appearance , central obesity , metabolic syndrome etc) These drugs cause LIPODYSTROPHY SYNDROME by - | GLUCOSE | LIPIDS INSULIN RESISTANCE WT. GAIN. - These include drugs like: INDINAVIR RITONAVIR LOPINAVIR AMPRENAVIR FOS-AMPRENAVIR ATAZANAVIR (Lowest risk of Lipodystrophy syndrome but can cause hyperbilrubinemia) SAQUINAVIR NELFINAVIR Abacavir, Entecavir and Adefovir - NI (Nucleoside reverse transcriptase inhibitors)
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