Which among the following is the function of cholesterol in the Plasmalemma:
Correct Answer: Decrease fluidity of the lipid bilayer
Description: The fluidity of the lipid bilayer is decreased in 3 ways: (1) By lowering the temperature, (2) By increasing the saturation of the fatty acyl tails of the phospholipid molecules, and (3) By increasing the membrane's cholesterol content Cholesterol interacts with phospholipids containing unsaturated fatty acyl chains, compacting them and constraining their motion in bilayers, hence decreases the fluidity.
Category:
Biochemistry
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