What is the primary toxicity of doxorubicin (Adriamycin)?
Correct Answer: Cardiomyopathy
Description: Doxorubicin, an antibiotic derived from Streptomyces species, has activity against sarcomas and carcinomas of the breast, liver, bladder, prostate, head and neck, esophagus, and lung. Its major side effect is production of a dilated cardiomyopathy. Patients receiving this agent should have echocardiography before and after treatment in order to monitor potential cardiac toxicity.
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Surgery
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