What is the most important good prognostic factor for neuroblastoma?
Correct Answer: CD44 expression
Description: Ans. is 'd' i.e., CD44 expression Prognostic Factors in NeuroblastomasVariableFavorableUnfavorableStageStage 1, 2A, 2B, 4SStage 3, 4Age< 1 year> 1 yearHistology * Evidence of schwannian stroma and gangliocytic differentiationPresentAbsent* Mitotic rateLowHigh* Mitosis-karhorrhexis index< 200/500 cells> 200/500 ceils* Intratumoral calcificationPresentAbsentDNA ploidyHyperdiploid or near-triploidDiploid, near-diploid or near-tetraploidN-mycNot amplifiedAmplifiedChromosome 17q GainAbsentPresentChromosome 1p LossAbsentPresentChromosome 1 1q lossAbsentPresentTrK - B expressionAbsentPresentTrk-A ExpressionPresentAbsentTelomerase ExpressionLow or absentHighly expressedMRP ExpressionAbsentPresentCD-44 ExpressionPresentAbsentSerum Biochemical Markers * FerritinNormalElevated* Lactate Dehydrogenase< 1500U/mL> 1500 U/mL
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now