Biochemistry What is the function of DNA ligase ? A Unwinding (denaturation) of dsDNA to provide an ssDNA template B Seals the single strand nick between the nascent chain and Okazaki fragments on lagging strand C Initiation of DNA synthesis and elongation D Initiates synthesis of RNA primers 💡 Explanation What is the function of DNA ligase ? ✓ Correct Answer: B. Seals the single strand nick between the nascent chain and Okazaki fragments on lagging strand