What is the cause of hypercoagulation in nephrotic syndrome:
Correct Answer: Loss of antithrombin III (AT III)
Description: Thrombotic and thromboembolic complications are common in nephrotic syndrome due to loss of anticoagulant factor (e.g. antithrombin III, protein C and S) combined with increased platelet activation. Renal vein thrombosis is most often a consequence of this hypercoagulative state. There is also increased synthesis of fibrinogen in the liver.
Category:
Pathology
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