What is the amount of trisodium citrate dihydrate in WHO ORS ?
**Core Concept**
The World Health Organization (WHO) Oral Rehydration Solution (ORS) is a crucial tool in the management of dehydration, particularly in cases of diarrhea. The formula of ORS involves a specific concentration of electrolytes to maintain fluid and electrolyte balance in the body.
**Why the Correct Answer is Right**
Trisodium citrate dihydrate is an essential component of the WHO ORS, serving as a buffer to maintain the pH of the solution and prevent acidosis. It helps in stabilizing the bicarbonate concentration, thereby facilitating the absorption of sodium and water in the intestinal tract. The correct amount of trisodium citrate dihydrate in WHO ORS is crucial for its effectiveness.
**Why Each Wrong Option is Incorrect**
**Option A:** This is incorrect because the incorrect concentration of trisodium citrate dihydrate may disrupt the pH balance and impair the absorption of sodium and water.
**Option B:** This is incorrect as the specified amount is not in line with the WHO ORS formula, which could lead to suboptimal treatment outcomes.
**Option C:** This is incorrect due to the incorrect concentration of trisodium citrate dihydrate, which may cause acidosis in patients.
**Clinical Pearl / High-Yield Fact**
It is essential to remember that the correct concentration of trisodium citrate dihydrate in WHO ORS is critical for its efficacy, and any deviation from the recommended amount may lead to treatment failure or adverse effects.
**Correct Answer: C. 2.9 g/L**