What is phacoanaphylactic Uveitis?
Correct Answer: Uveitis as a result of lens tissue induced inflam mation following cataract surgery
Description: Ans. is 'a' i.e., Uveitis as a result of lens tissue induced inflam mation following cataract surgery o Due to cataract extraction or lens trauma, lens matter induces inflammation in the uveal tissue, called phacoanaphylactic/phacotoxic uveitis:# Phacoanaphylaxis/lens-induced uveitis occurs in the setting of a ruptured or degenerative lens capsule and is characterized by a granulomatous antigenic reaction to lens protein.# Lens proteins are most likely immunologically privileged, and they may initiate an immunologic sensitization only after entering the aqueous humor. This privilege is probably because of numerous factors, as follows: lens proteins are isolated from the fetal circulation early in embryonic life, the lens is devoid of innervation, and the adult lens is completely avascular.
Category:
Ophthalmology
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