Pharmacology What is mechanism of action of colchicine in acute gout? A Inhibition of leukotriene B4 B Inhibition of release of chemotactic factors C Binding to tubulin and inhibition of leucocyte migration D Promotes metabolism of urate crystal 💡 Explanation What is mechanism of action of colchicine in acute gout? ✓ Correct Answer: C. Binding to tubulin and inhibition of leucocyte migration