What is involved in the formation of d-TMP from d-UMP?
Correct Answer: N5, N10-methylene tetrahydrofolate
Description: The following reaction is catalyzed by thymidylate synthetase:5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMPBy means of reductive methylation, deoxyuridine monophosphate (dUMP) and N5, N10-methylene tetrahydrofolate together used to form dTMP, yielding dihydrofolate as a secondary product.
Category:
Biochemistry
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