**Core Concept**
Gastroschisis and omphalocele are two congenital abdominal wall defects that occur during embryonic development. Gastroschisis is a small defect in the anterior abdominal wall, usually to the right of the umbilicus, whereas omphalocele is a herniation of the intestines through a defect in the navel.

**Why the Correct Answer is Right**
Gastroschisis typically has no associated anomalies, whereas omphalocele often has associated anomalies due to the disruption of the development of the abdominal wall and the intestines. In omphalocele, the intestines are herniated into a sac, which may contain other abdominal contents such as the liver or bladder. Gastroschisis usually involves a small defect in the anterior abdominal wall, without any sac or herniation of abdominal contents.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as gastroschisis is typically to the right of the umbilicus, whereas omphalocele is usually in the midline.
**Option B:** This option is incorrect as gastroschisis usually has no associated anomalies, whereas omphalocele often has associated anomalies.
**Option C:** This option is incorrect as gastroschisis involves a small defect in the anterior abdominal wall without a sac, whereas omphalocele involves a herniation of the intestines through a defect in the navel with a sac.
**Option D:** This option is incorrect as gastroschisis is usually an isolated defect, whereas omphalocele often has associated anomalies.

**Clinical Pearl / High-Yield Fact**
It's essential to differentiate between gastroschisis and omphalocele, as gastroschisis typically has a better prognosis and outcome compared to omphalocele.

**Correct Answer: B. gastroschisis usually has no associated anomalies, whereas omphalocele often has associated anomalies.**