What does Hirschsprung’s disease involve? SELECT ONE.
Correct Answer: Meissner and Auerbach plexus deficiency
Description: In Hirschsprung's disease, there is an absence of myenteric plexus in the upper anal segment (i.e., the most distal portion of the cloaca). In 15%, the myenteric plexus involves only the upper anus; in 70%, the rectum is also involved; and in 15%, part of the colon is also involved. The abnormal segment is contracted; whereas, the dilated bowel is proximal to the diseased segment.
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