Warfarin to be stopped____________ days before surgery?
Correct Answer: 4 to 5 days
Description: Ans. is 'b' i.e., 4 to 5 days Warfarin may increase peri- operative bleeding, except for minor procedures such as cataract surgery without bulbar blocks. No consensus exists on the optimal perioperative management of patients receiving warfarin. The usual recommendation is to withhold warfarin staing 4 to 5 days preoperatively (if the INR is between 2.0 and 3.0) to allow the INR to decrease to less than 1.5, which is a level considered safe for surgical procedures and neuraxial blockade. If the INR is greater than 3.0, it is usually necessary to withhold warfarin longer than 4 to 5 days. If the INR is measured the day before the surgical procedure and remains higher than 1.8, a small dose of vitamin K (1 to 5 mg administrated orally or subcutaneously) can reverse anticoagulation. Vitamin K has an effect within 6 to 10 hours after oral or subcutaneous administration (more predictable with oral administration), and it peaks within 24 hours to 48 hours. Administration of higher doses may lead to warfarin resistance when therapy is initiated again.
Category:
Anaesthesia
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now