Vitamin K is given to a patient with jaundice, but PT remains unchanged. Probable cause is

Correct Answer: Cirrhosis
Description: An elevated prothrombin time indicates either vitamin K deficiency due to prolonged jaundice and malabsorption of vitamin K or significant hepatocellular dysfunction. The failure of the prothrombin time to correct with parenteral administration of vitamin K indicates severe hepatocellular injuryReference: Harrison&;s Principles of Internal Medicine; 19th edition; Chapter 58; Jaundice
Category: Medicine
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