Vitamin C is the co-enzyme for the following hydroxylases EXCEPT
Correct Answer: Aspartate betahydroxylase
Description: -Vitamin C plays the role of a coenzyme in hydroxylation of proline and lysine while protocollagen is converted to collagen (i.e. post-translational modification). The hydroxylation reaction is catalysed by lysyl hydroxylase (for lysine) and prolyl hydroxylase (for proline).
-Hydroxylation of glycine is carried out by peptidylglycine hydroxylase which requires vitamin C.
-Ascorbic acid is required for the oxidation of p-hydroxy phenylpyruvate (enzyme hydroxylase) to homogentisic acid in tyrosine metabolism.
Category:
Biochemistry
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