Vitamin-A solution contains
**Core Concept**
Vitamin A solutions, often used in ophthalmology for corneal ulcers or retinal degeneration, are typically derived from retinol or retinaldehyde. These derivatives are essential for maintaining corneal integrity and promoting epithelialization.
**Why the Correct Answer is Right**
The correct answer is a preservative used in these solutions. The most common preservative is benzalkonium chloride, which inhibits microbial growth by disrupting cell membranes. This allows the Vitamin A solution to remain sterile for a longer period, ensuring patient safety. Benzalkonium chloride also helps prevent the degradation of retinol or retinaldehyde, maintaining the solution's potency.
**Why Each Wrong Option is Incorrect**
**Option A:** **Chlorhexidine** - While chlorhexidine is a disinfectant and antiseptic, it is not commonly used as a preservative in Vitamin A solutions due to its potential toxicity and cytotoxic effects on ocular tissues.
**Option B:** **Glycerin** - Glycerin is sometimes added to ophthalmic solutions to help maintain osmotic balance, but it is not a preservative and does not inhibit microbial growth.
**Option C:** **EDTA** - EDTA (ethylenediaminetetraacetic acid) is a chelating agent used in some ophthalmic solutions to remove calcium and magnesium ions, which can contribute to microbial growth. However, it is not typically used as a preservative in Vitamin A solutions.
**Clinical Pearl / High-Yield Fact**
When selecting ophthalmic solutions, it is crucial to choose products with preservatives that are compatible with the specific application and patient population. For example, benzalkonium chloride may be contraindicated in patients with certain allergies or sensitivities.
**Correct Answer: B. Benzalkonium chloride**