**Core Concept**
In volume-cycled ventilation, the inspiratory flow rate is determined by the ventilator's ability to deliver a set tidal volume efficiently, relying on the patient's airway resistance and compliance. The flow rate must be high enough to ensure rapid delivery of gas but not so high as to cause barotrauma or excessive peak pressures.

**Why the Correct Answer is Right**
In volume-cycled ventilation, the inspiratory flow rate is typically set between **60–100 L/min** to achieve a rapid rise in inspiratory flow, ensuring efficient delivery of the preset tidal volume within a short time. This range balances effective ventilation with safe pressure limits. The flow rate is calculated based on the patient’s anatomical dead space and desired tidal volume, with a standard flow rate of 60–100 L/min being optimal for most adult patients during mechanical ventilation.

**Why Each Wrong Option is Incorrect**
Option A: 140–160 L/min — This flow rate is extremely high and can cause barotrauma, excessive peak airway pressures, and increased risk of lung injury. It is not standard in routine volume-cycled ventilation.
Option B: 110–130 L/min — Still too high for safe use; exceeds typical safe limits and increases risk of airway injury and patient discomfort.
Option D: 30–50 L/min — This is too low to deliver a sufficient tidal volume quickly, leading to prolonged inspiratory time and poor ventilation efficiency.

**Clinical Pearl / High-Yield Fact**
In volume-cycled ventilation, a flow rate of **60–100 L/min** is standard for adult patients; flow rates below 60 L/min may result in inadequate delivery of tidal volume, while rates above 100 L/min increase the risk of airway trauma and barotrauma.

✓ Correct Answer: C. 60-100 L/min