**Core Concept**
Inactivated vaccines are generally safe for use in immunocompromised individuals, but live attenuated vaccines can pose a risk due to the potential for transmission of the live virus. This is particularly concerning in individuals with weakened immune systems, such as those with immunodeficiency disorders.
**Why the Correct Answer is Right**
The correct answer is related to the use of live attenuated vaccines in individuals with immunodeficiency disorders, such as those with severe combined immunodeficiency (SCID). Live attenuated vaccines contain a weakened form of the virus, which can cause a mild infection in healthy individuals but can be severe or even life-threatening in immunocompromised individuals. In these cases, the risk of vaccine-associated infection outweighs the benefits of vaccination.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because inactivated vaccines are not typically contraindicated in immunocompromised individuals.
**Option B:** This option is incorrect because the specific vaccine type is not specified, making it a vague and incorrect answer.
**Option C:** This option is incorrect because it does not specify a particular vaccine or scenario, making it an ambiguous and incorrect answer.
**Clinical Pearl / High-Yield Fact**
Live attenuated vaccines should be avoided in immunocompromised individuals due to the risk of vaccine-associated infection. Inactivated vaccines are generally safer alternatives in these cases.
**Correct Answer:** D. Live attenuated vaccines are contraindicated in immunocompromised individuals.
Free Medical MCQs · NEET PG · USMLE · AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.