Vaccination causing intussusception: (PGI Dec 2007)
**Core Concept**
The question tests the understanding of vaccine-related adverse effects, specifically the association between certain vaccines and **intussusception**, a condition where a part of the intestine folds into the section next to it. This condition can lead to bowel obstruction and ischemia if not treated promptly.
**Why the Correct Answer is Right**
The correct answer is related to the **rotavirus vaccine**, which has been associated with an increased risk of intussusception, particularly in the first week after vaccination. The mechanism is not entirely understood, but it's thought to be related to the vaccine's ability to cause a mild intestinal inflammation, which can lead to intussusception in susceptible individuals.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect because it does not specify a vaccine known to cause intussusception.
**Option B:** Incorrect as it is not directly linked to intussusception as a common adverse effect.
**Option C:** Incorrect because, although vaccines can have various side effects, this option does not accurately represent the specific risk of intussusception.
**Clinical Pearl / High-Yield Fact**
It's crucial to remember that the benefits of vaccination far outweigh the risks, including the risk of intussusception from the rotavirus vaccine. Monitoring for signs of intussusception after vaccination is essential.
**Correct Answer:** D. Rotavirus vaccine.