Unfamiliarity of familiar things is seen in :
**Core Concept**
Familiarity and unfamiliarity of familiar things are key concepts in the study of psychopathology, particularly in the realm of memory and perception. **Jamais vu** is a phenomenon where a familiar situation or event is perceived as strange or unfamiliar, despite being experienced before.
**Why the Correct Answer is Right**
Jamais vu is characterized by a feeling of unfamiliarity with a familiar situation or event, often accompanied by a sense of detachment or estrangement. This phenomenon is thought to be related to a disruption in the normal functioning of memory, particularly in the process of consolidation and retrieval. In normal circumstances, memories are consolidated and retrieved through a process involving the hippocampus, amygdala, and prefrontal cortex. However, in individuals experiencing jamais vu, this process is disrupted, leading to a sense of unfamiliarity with familiar events.
**Why Each Wrong Option is Incorrect**
**Option A:** Deja vu is the opposite of jamais vu, where a familiar situation or event is perceived as familiar or repetitive, often accompanied by a sense of familiarity or nostalgia.
**Option C:** Deja entendu is a French term that refers to the feeling of familiarity with a phrase or sentence that has never been heard before, often accompanied by a sense of familiarity or recognition.
**Option D:** Deja pence is not a recognized term in psychiatry and appears to be a distractor.
**Clinical Pearl / High-Yield Fact**
Jamais vu is often associated with temporal lobe epilepsy, particularly in the context of mesial temporal lobe epilepsy, which can lead to a disruption in the normal functioning of memory and perception.
**β Correct Answer: B. Jamais vu**