Type I hypersensitivity includes all of the following except:
Correct Answer: Autoimmune hemolytic anemia
Description: Ans. is 'a' i.e., Autoimmune hemolytic anemia (Ref: Ananthanarayan, 9th/e, p. 162 and 8th/e, p. 162)* Autoimmune hemolytic anemia is type II HSN.* In type II Hypersensitivity reaction (Ab mediated) various mechanisms involves up: (1) Opsonization, complement and Fc receptor mediated phagocytosis (C3b acts as opsonin). (2) Complement and Fc receptor mediated inflammation (C5a acts as chemokine for neutrophil and monocyte. (3) Antibody mediated cellular dysfunction.
Category:
Microbiology
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