Turner’s syndrome karyotyping is –

**Core Concept**
Turner's syndrome is a genetic disorder affecting females, characterized by the presence of one X chromosome and the absence of a second sex chromosome. This chromosomal abnormality leads to various physical and developmental issues.

**Why the Correct Answer is Right**
The correct karyotype for Turner's syndrome is 45,X, indicating the presence of only one X chromosome. This occurs due to a deletion or loss of the second sex chromosome during meiosis. The absence of the second sex chromosome disrupts the normal balance of sex chromosomes, leading to the characteristic features of Turner's syndrome, including short stature, infertility, and cardiovascular abnormalities.

**Why Each Wrong Option is Incorrect**
**Option A:** 46,XY - This karyotype is associated with Klinefelter syndrome, a genetic disorder affecting males with an extra X chromosome.
**Option B:** 47,XXY - This karyotype is also associated with Klinefelter syndrome, indicating an extra X chromosome in males.
**Option C:** 47,XXX - This karyotype is associated with triploidy or trisomy X, a rare genetic condition affecting females with an extra X chromosome.

**Clinical Pearl / High-Yield Fact**
Turner's syndrome is often associated with a characteristic "bifid" or split sternum, which can be a useful clinical clue for diagnosing this condition.

**Correct Answer: C. 47,XXX**