Tumor that follows rule of 10 is-
**Core Concept**
The "rule of 10" in oncology refers to a tumor that metastasizes to a new site within 10 years of its original diagnosis, involves 10% or more of the organ or structure it originates from, and has a 10% chance of causing death within 10 years of diagnosis. This concept is particularly relevant in the context of neuroblastoma, a type of pediatric cancer.
**Why the Correct Answer is Right**
The correct answer is a type of tumor that follows this rule. Neuroblastoma, a cancer of the sympathetic nervous system, often adheres to the rule of 10. It commonly metastasizes to the bones, bone marrow, liver, and lymph nodes within 10 years of diagnosis, involves 10% or more of the adrenal gland or other organs, and has a 10% chance of causing death within 10 years. This is due to the tumor's ability to invade and infiltrate surrounding tissues, as well as its potential to spread to distant sites through the bloodstream and lymphatic system.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not specifically relate to the "rule of 10." While some other cancers may exhibit similar characteristics, they do not adhere to this specific criterion.
**Option B:** This option is incorrect because it does not fit the rule of 10. The characteristics of this tumor do not align with the criteria set forth by the rule.
**Option C:** This option is incorrect because it does not follow the rule of 10. The tumor's behavior and potential for metastasis do not meet the criteria established by this rule.
**Clinical Pearl / High-Yield Fact**
The rule of 10 is an important concept in oncology, as it helps clinicians predict the behavior and prognosis of certain tumors. By understanding the characteristics of tumors that follow this rule, healthcare providers can better manage patient care and make informed decisions about treatment.
**Correct Answer:** C. Neuroblastoma