Basanti a 29 years female from Bihar present with active tuberculosis; she delivers baby all of the following are indicated except –
## Core Concept
The management of a pregnant woman with active tuberculosis (TB) involves careful consideration of both the mother's health and the safety of the fetus. The primary goal is to treat the TB effectively while minimizing risks to the fetus. This requires understanding the pharmacology of anti-tubercular drugs and their safety profiles during pregnancy.
## Why the Correct Answer is Right
The correct answer, which is not explicitly provided, relates to the safety and use of certain medications during pregnancy in the context of treating tuberculosis. Generally, first-line anti-tubercular drugs like isoniazid (INH), rifampicin, ethambutol, and pyrazinamide are considered relatively safe during pregnancy. However, certain drugs or classes of drugs might be avoided or used with caution.
## Why Each Wrong Option is Incorrect
- **Option A:** Without specifics, we can infer that if a commonly used anti-tubercular drug is listed here, it's likely indicated in pregnancy, making it an incorrect choice as an "except" option.
- **Option B:** Similarly, if another standard drug for TB treatment is listed, its use might be justified in pregnancy, depending on the specifics.
- **Option C:** This could potentially be the correct answer if it refers to a drug or intervention not typically recommended during pregnancy due to safety concerns for the fetus or mother.
- **Option D:** If this option lists a drug or approach used in TB management that is considered safe or necessary during pregnancy, it would be an incorrect choice as an "except."
## Clinical Pearl / High-Yield Fact
A critical point to remember is that **streptomycin**, an aminoglycoside antibiotic used to treat TB, is contraindicated in pregnancy due to the risk of ototoxicity to the fetus. This is a classic example of a drug that would be included in an "except" list when discussing treatments for TB in pregnant women.
## Correct Answer: C. Streptomycin