Tryptophan is required for synthesis of which vitamin?
Correct Answer: Niacin
Description: Tryptophan is required for the synthesis of Niacin. In the major pathway, kynureninase is an enzyme dependent on pyridoxal phosphate (enzyme 2, Fig.17.8). Therefore, in vitamin B6 deficiency, the pathway is blocked at this level. This leads to niacin deficiency and manifestations of pellagra. 7. Quinolinate phosphoribosyl transferase is the rate-limiting enzyme in the conversion of niacin to NAD+. About 60 mg of tryptophan is equivalent to 1 mg of niacin. Reference: Vasudevan Textbook of Biochemistry pg no. 211, 395
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now