Tryptophan is glucogenic & ketogenic by producing
Correct Answer: Acetyl CoA & alanine
Description: The major metabolic fate of tryptophan is to be oxidized by tryptophan pyrrolase (tryptophan di-oxygenase) (Step 1, Fig. 17.8). It is a hemoprotein. The enzyme is inducible by coicosteroids.iii. In this major pathway, the total 11 carbon atoms of tryptophan are catabolized as formyl group (1C which enters the one-carbon pool), alanine (3C, entering the glucose pathway) and acetoacetate (4C, going to ketogenic pathway). So, tryptophan is both glucogenic and ketogenic. The remaining 3 carbons are removed as 3 CO2 molecules.Ref: DM Vasudevan - Textbook of Biochemistry, 6th edition, page no: 211
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now