True statements regarding DMPA includes all the following except
**Core Concept**
DMPA (Depot Medroxyprogesterone Acetate) is a long-acting reversible contraceptive injection used to prevent pregnancy. It works by inducing a state of anovulatory cycles, thickening cervical mucus, and thinning the endometrium, making it inhospitable for implantation.
**Why the Correct Answer is Right**
DMPA acts by suppressing gonadotropin release from the pituitary gland, leading to decreased estrogen levels and subsequently inhibiting follicular growth in the ovaries. This results in anovulatory cycles, which prevent ovulation and fertilization. The injection also causes thickening of cervical mucus, making it difficult for sperm to penetrate, and thinning of the endometrium, reducing the chance of implantation.
**Why Each Wrong Option is Incorrect**
**Option A:** DMPA is not contraindicated in breastfeeding women, but it may affect milk production. However, it is not the correct answer as the question asks for an exception.
**Option B:** DMPA is a progestin-only contraceptive, and it does not contain estrogen. This is a true statement regarding DMPA.
**Option C:** DMPA is a long-acting reversible contraceptive, and it is not a permanent method of birth control. This is a true statement regarding DMPA.
**Clinical Pearl / High-Yield Fact**
DMPA is a popular choice for family planning due to its convenience, high efficacy, and long duration of action. However, it may cause irregular bleeding patterns and changes in libido during the initial months of use.
**Correct Answer:** A.