True regarding tetanus toxoid is/are –
## Core Concept
Tetanus toxoid is a vaccine used to prevent tetanus, a bacterial infection caused by *Clostridium tetani*. The toxoid works by inducing immunity against the tetanus toxin, which is produced by the bacteria. This immunity prevents the toxin from causing the disease.
## Why the Correct Answer is Right
The correct answer involves understanding the characteristics and uses of tetanus toxoid. Tetanus toxoid is made from the toxin produced by *Clostridium tetani*, which is inactivated to prevent it from causing disease. This inactivated toxin stimulates the body to produce antibodies that can neutralize the toxin, providing immunity against tetanus. Tetanus toxoid is commonly administered as part of routine childhood vaccination and booster shots are given periodically to maintain immunity.
## Why Each Wrong Option is Incorrect
- **Option A:** Without the specific details of option A, we cannot directly address its inaccuracies. However, any incorrect statement about tetanus toxoid could involve its composition, method of action, or clinical use.
- **Option B:** Similarly, without specifics, we can't directly refute option B. Generally, incorrect options might claim tetanus toxoid is ineffective, describe a wrong method of production, or suggest incorrect dosing schedules.
- **Option C:** This option's inaccuracy would depend on its content. If it suggests tetanus toxoid provides immediate immunity or is not suitable for certain populations, it could be incorrect based on the vaccine's pharmacodynamics and recommended usage.
## Clinical Pearl / High-Yield Fact
A key point to remember is that tetanus toxoid is often given in combination with other vaccines, such as diphtheria toxoid and pertussis vaccine (DTaP), and that booster shots are crucial for maintaining immunity. A classic clinical correlation is that tetanus-prone wounds in individuals with uncertain vaccination history may require immediate vaccination and/or tetanus immunoglobulin.
## Correct Answer: D.