True about Wallerian degeneration
Correct Answer: None
Description: Distal (Wallerian) degeneration: mediated by calcium influx and activation of axonal proteases 24 hours:neurofilaments break up and the axon fragments into sho lengths. Within 10 days:myelin decomposes into fat droplets (after 10 days, Schwann cells begins to fragment myelin sheath.....a change from myelinating to demyelinating) In 3 months: macrophages phagocytose the debris, leaving behind only endoneural tube/ ghost tube (filled by the rapidly multiplying Schwann cell's cytoplasm)
Category:
Physiology
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