Biochemistry True about the Sickle cell disease are all, Except – A Single nucleotide change results in change of Glutamate to Valine B Sticky patch is generated as a result of replacement of a non polar residue with a polar residue C HbS confers resistance against malaria in heterozygotes D RFLP results from a single base change 💡 Explanation True about the Sickle cell disease are all, Except - ✓ Correct Answer: B. Sticky patch is generated as a result of replacement of a non polar residue with a polar residue