True about telomerase or telomere is/area) They are present at the ends of eukaryotic chromosomeb) Increased telomerase activity favours cancer cellsc) DNA dependent RNA polymerased) DNA polymerase
Correct Answer: ab
Description: Telomers are short repeated sequence of DNA at the end of chromosomes.
In normal somatic cells, telomers get shortened in each replicated cycle, and after telomers are shortened by a critical length, cell stops dividing and enters into senescence (Go phase).
However, Germ cells, cancer cells and stem cells have an enzyme telomerase which prevents telomer shortening so that these cells have ability to self replicate extensively.
Telomerase is a reverse transcriptase (RNA dependent NA polymerase).
Category:
Biochemistry
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